There are reports of significant age-related decreases in the chromium concentrations of hair, sweat and blood,1 which might suggest that older people are more vulnerable to chromium depletion than younger adults.2 One cannot be sure, however, as chromium status is difficult to determine.3 That's because blood, urine, and hair levels do not necessarily reflect body stores.4 5 Furthermore, no chromium-specific enzyme or other biochemical marker has been found to reliably assess a person's chromium status.6 7
There is considerable interest in the possibility that supplemental chromium may help to treat impaired glucose tolerance and type 2 diabetes, but the research to date is inconclusive. No large, randomized, controlled clinical trials testing this hypothesis have been reported in the United States.8 Nevertheless, this is an active area of research.
Related Links: What is chromium? | What foods provide chromium? | How much chromium do I need? | What happens if I do not get enough chromium? | Do I need extra chromium? | Can chromium be harmful? | What are some current issues and controversies about chromium? | Does chromium interact with any medicines or supplements? |
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The mission of the Office of Dietary Supplements (ODS) is to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, stimulating and supporting research, disseminating research results, and educating the public to foster an enhanced quality of life and health for the U.S. population.
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The information is not intended to be a substitute for professional medical advice. It is important to seek the advice of a physician about any medical condition or symptom. It is also important to seek the advice of a physician, registered dietitian, pharmacist, or other qualified health professional about the appropriateness of taking dietary supplements and their potential interactions with medications.
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Footnotes
- Davies S, Howard JM, Hunnisett A, Howard M. Age-related decreases in chromium levels in 51,665 hair, sweat, and serum samples from 40,872 patients — implications for the prevention of cardiovascular disease and type II diabetes mellitus. Metabolism 1997;46:469-73. [↩]
- Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington, DC, 2001. [↩]
- Gibson RS. Principles of Nutritional Assessment, 2nd Edition. Oxford University Press, New York, 2005. [↩]
- Lukaski HC. Chromium as a supplement. Annu Rev Nutr 1999;19:279-302. [↩]
- Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington, DC, 2001. [↩]
- Lukaski HC. Chromium as a supplement. Annu Rev Nutr 1999;19:279-302. [↩]
- Stoecker BJ. Chromium. In: Modern Nutrition in Health and Disease, 9th Edition (edited by Shils ME, Olson JA, Shike M, Ross AC.) Lippincott Williams and Wilkins, New York, 1999, pp. 277-282. [↩]
- Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington, DC, 2001. [↩]
